| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | WASF3 |
| Gene ID: | 10810 |
| Uniprot ID: | WASF3_HUMAN |
| Immunogen Region: | 200-300 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human WASF3 (NP_001278894.1). |
| Immunogen Sequence: | RTRKEEWERRKMGIEFMSDA KKLEQAGSAKEDRVPSGSHA SDVTDYSYPATPNHSLHPQP VTPSYAAGDVPPHGPASQAA EHEYRPPSASARHMALNRPQ Q |
| Tissue Specificity | Expressed in ovary and brain. |
| Post Translational Modifications | Phosphorylation by ABL1 promotes lamellipodia formation and cell migration. |
| Function | Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. |
| Protein Name | Actin-Binding Protein Wasf3Protein Wave-3Verprolin Homology Domain-Containing Protein 3Wiskott-Aldrich Syndrome Protein Family Member 3Wasp Family Protein Member 3 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Actin-Binding Protein Wasf3 antibodyAnti-Protein Wave-3 antibodyAnti-Verprolin Homology Domain-Containing Protein 3 antibodyAnti-Wiskott-Aldrich Syndrome Protein Family Member 3 antibodyAnti-Wasp Family Protein Member 3 antibodyAnti-WASF3 antibodyAnti-KIAA0900 antibodyAnti-SCAR3 antibodyAnti-WAVE3 antibody |
Information sourced from Uniprot.org
