| Short Description : | Goat polyclonal antibody anti-VTI1B (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 26-28kDa band observed in Human Duodenum, Kidney and Testes lysates (calculated MW of 26.7kDa according to NP_006361.1). Recommended concentration: 1-3µg/ml. |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | VTI1B |
| Gene ID: | 10490 |
| Uniprot ID: | VTI1B_HUMAN |
| Accession Number: | NP_006361.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | RDFDEKQQEANET |
| Function | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. |
| Protein Name | Vesicle Transport Through Interaction With T-Snares Homolog 1bVesicle Transport V-Snare Protein Vti1-Like 1Vti1-Rp1 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Early Endosome MembraneSingle-Pass Type Iv Membrane ProteinLate Endosome MembraneLysosome MembraneCytoplasmic GranuleRecycling Endosome Membrane |
| Alternative Antibody Names | Anti-Vesicle Transport Through Interaction With T-Snares Homolog 1b antibodyAnti-Vesicle Transport V-Snare Protein Vti1-Like 1 antibodyAnti-Vti1-Rp1 antibodyAnti-VTI1B antibodyAnti-VTI1 antibodyAnti-VTI1L antibodyAnti-VTI1L1 antibodyAnti-VTI2 antibody |
Information sourced from Uniprot.org
