| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VTI1B |
| Gene ID: | 10490 |
| Uniprot ID: | VTI1B_HUMAN |
| Immunogen Region: | 1-210 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human VTI1B (NP_006361.1). |
| Immunogen Sequence: | MASSAASSEHFEKLHEIFRG LHEDLQGVPERLLGTAGTEE KKKLIRDFDEKQQEANETLA EMEEELRYAPLSFRNPMMSK LRNYRKDLAKLHREVRSTPL TATPGGRGDMKYGIYAVENE HMNRLQSQRAMLLQGTESLN RATQSIERSHRIATETDQIG SEIIEELGEQRDQLERTKSR LVNTSENLSKSRKILRSMSR KVTTNKLLLS |
| Tissue Specificity | Expressed in all tissues examined. |
| Function | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. |
| Protein Name | Vesicle Transport Through Interaction With T-Snares Homolog 1bVesicle Transport V-Snare Protein Vti1-Like 1Vti1-Rp1 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Early Endosome MembraneSingle-Pass Type Iv Membrane ProteinLate Endosome MembraneLysosome MembraneCytoplasmic GranuleRecycling Endosome Membrane |
| Alternative Antibody Names | Anti-Vesicle Transport Through Interaction With T-Snares Homolog 1b antibodyAnti-Vesicle Transport V-Snare Protein Vti1-Like 1 antibodyAnti-Vti1-Rp1 antibodyAnti-VTI1B antibodyAnti-VTI1 antibodyAnti-VTI1L antibodyAnti-VTI1L1 antibodyAnti-VTI2 antibody |
Information sourced from Uniprot.org