| Function | Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein Vta1 HomologDopamine-Responsive Gene 1 ProteinDrg-1Lyst-Interacting Protein 5Lip5Skd1-Binding Protein 1Sbp1 |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-917729 |
| Cellular Localisation | CytoplasmEndosome MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein Vta1 Homolog antibodyAnti-Dopamine-Responsive Gene 1 Protein antibodyAnti-Drg-1 antibodyAnti-Lyst-Interacting Protein 5 antibodyAnti-Lip5 antibodyAnti-Skd1-Binding Protein 1 antibodyAnti-Sbp1 antibodyAnti-VTA1 antibodyAnti-C6orf55 antibodyAnti-HSPC228 antibodyAnti-My012 antibody |
Information sourced from Uniprot.org
