| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-V-type immunoglobulin domain-containing suppressor of T-cell activation is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VSIR |
| Gene ID: | 64115 |
| Uniprot ID: | VISTA_HUMAN |
| Specificity: | This antibody detects endogenous levels of VISTA at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human VISTA |
| Post Translational Modifications | At the cell surface, may be cleaved by MMP14. N-glycosylated. |
| Function | Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation. |
| Protein Name | V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation Platelet Receptor Gi24 Stress-Induced Secreted Protein-1 Sisp-1 V-Set Domain-Containing Immunoregulatory Receptor V-Set Immunoregulatory Receptor |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation antibody Anti-Platelet Receptor Gi24 antibody Anti-Stress-Induced Secreted Protein-1 antibody Anti-Sisp-1 antibody Anti-V-Set Domain-Containing Immunoregulatory Receptor antibody Anti-V-Set Immunoregulatory Receptor antibody Anti-VSIR antibody Anti-C10orf54 antibody Anti-SISP1 antibody Anti-VISTA antibody Anti-PP2135 antibody Anti-UNQ730 antibody Anti-PRO1412 antibody |
Information sourced from Uniprot.org