| Tissue Specificity | Expressed in red blood cells (at protein level). Widely expressed, with high expression in brain, heart, skeletal muscle and kidney. |
| Function | Mediates the transfer of lipids between membranes at organelle contact sites. Binds phospholipids. Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria. Negatively regulates lipid droplet size and motility. Required for efficient lysosomal protein degradation. |
| Protein Name | Intermembrane Lipid Transfer Protein Vps13aChorea-Acanthocytosis ProteinChoreinVacuolar Protein Sorting-Associated Protein 13a |
| Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneEndosome MembraneLysosome MembraneLipid DropletGolgi ApparatusCytoplasmic VesicleSecretory VesicleNeuronal Dense Core VesicleLocalizes At Mitochondria-Endosomes And Mitochondria-Endoplasmic Reticulum Contact Sites |
| Alternative Antibody Names | Anti-Intermembrane Lipid Transfer Protein Vps13a antibodyAnti-Chorea-Acanthocytosis Protein antibodyAnti-Chorein antibodyAnti-Vacuolar Protein Sorting-Associated Protein 13a antibodyAnti-VPS13A antibodyAnti-CHAC antibodyAnti-KIAA0986 antibody |
Information sourced from Uniprot.org
