Anti-VIPR2 antibody (83-132 aa) (STJ96253)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human VIPR2 at the amino acid range 83-132
General Information
| Short Description | Rabbit polyclonal anti-Vasoactive intestinal polypeptide receptor 2 (83-132 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VIPR2 |
| Gene ID | 7434 |
| Uniprot ID | VIPR2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human VIPR2 at the amino acid range 83-132 |
| Immunogen Region | 83-132 aa |
| Specificity | VPAC2 Polyclonal Antibody detects endogenous levels of VPAC2 protein. |
Additional Info
| Function | G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of potency PACAP38 = VIP > PACAP27. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. May be coupled to phospholipase C. |
| Protein Name | Vasoactive Intestinal Polypeptide Receptor 2Vip-R-2Helodermin-Preferring Vip ReceptorPituitary Adenylate Cyclase-Activating Polypeptide Type Iii ReceptorPacap Type Iii ReceptorPacap-R-3Pacap-R3Vpac2 ReceptorVpac2r |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vasoactive Intestinal Polypeptide Receptor 2 antibodyAnti-Vip-R-2 antibodyAnti-Helodermin-Preferring Vip Receptor antibodyAnti-Pituitary Adenylate Cyclase-Activating Polypeptide Type Iii Receptor antibodyAnti-Pacap Type Iii Receptor antibodyAnti-Pacap-R-3 antibodyAnti-Pacap-R3 antibodyAnti-Vpac2 Receptor antibodyAnti-Vpac2r antibodyAnti-VIPR2 antibodyAnti-VIP2R antibody |
Information sourced from Uniprot.org