Anti-VIPR1/VPAC1 antibody [23A11] {APC} (STJA0029377)

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STJA0029377
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Host: Mouse
Applications: FC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Vasoactive Intestinal Polypeptide Receptor 1 for use in FC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 23A11
Conjugation: APC
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: VIPR1
Gene ID: 7433
Uniprot ID: VIPR1_HUMAN
Function G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway.
Protein Name Vasoactive Intestinal Polypeptide Receptor 1
Vip-R-1
Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor
Pacap Type Ii Receptor
Pacap-R-2
Pacap-R2
Vpac1 Receptor
Vpac1r
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Vasoactive Intestinal Polypeptide Receptor 1 antibody
Anti-Vip-R-1 antibody
Anti-Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor antibody
Anti-Pacap Type Ii Receptor antibody
Anti-Pacap-R-2 antibody
Anti-Pacap-R2 antibody
Anti-Vpac1 Receptor antibody
Anti-Vpac1r antibody
Anti-VIPR1 antibody

Information sourced from Uniprot.org