| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VIPR1 (31-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VIPR1 |
| Gene ID: |
7433 |
| Uniprot ID: |
VIPR1_HUMAN |
| Immunogen Region: |
31-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 31-150 of human VIPR1 (NP_004615.2). |
| Immunogen Sequence: |
ARLQEECDYVQMIEVQHKQC LEEAQLENETIGCSKMWDNL TCWPATPRGQVVVLACPLIF KLFSSIQGRNVSRSCTDEGW THLEPGPYPIACGLDDKAAS LDEQQTMFYGSVKTGYTIGY |
| Tissue Specificity | In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT. |
| Function | This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. |
| Protein Name | Vasoactive Intestinal Polypeptide Receptor 1Vip-R-1Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii ReceptorPacap Type Ii ReceptorPacap-R-2Pacap-R2Vpac1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vasoactive Intestinal Polypeptide Receptor 1 antibodyAnti-Vip-R-1 antibodyAnti-Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor antibodyAnti-Pacap Type Ii Receptor antibodyAnti-Pacap-R-2 antibodyAnti-Pacap-R2 antibodyAnti-Vpac1 antibodyAnti-VIPR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
