| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Voltage-dependent anion-selective channel protein 3 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VDAC3 |
| Gene ID: | 7419 |
| Uniprot ID: | VDAC3_HUMAN |
| Specificity: | VDAC3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
| Function | Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Involved in male fertility and sperm mitochondrial sheath formation. |
| Protein Name | Voltage-Dependent Anion-Selective Channel Protein 3Vdac-3Hvdac3Outer Mitochondrial Membrane Protein Porin 3 |
| Database Links | Reactome: R-HSA-5205685Reactome: R-HSA-5689880Reactome: R-HSA-8949215 |
| Cellular Localisation | Mitochondrion Outer MembraneMembraneMay Localize To Non-Mitochondrial Membranes |
| Alternative Antibody Names | Anti-Voltage-Dependent Anion-Selective Channel Protein 3 antibodyAnti-Vdac-3 antibodyAnti-Hvdac3 antibodyAnti-Outer Mitochondrial Membrane Protein Porin 3 antibodyAnti-VDAC3 antibody |
Information sourced from Uniprot.org