| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-U3 small nucleolar RNA-associated protein 25 homolog (296-346 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UTP25 |
| Gene ID: |
27042 |
| Uniprot ID: |
UTP25_HUMAN |
| Immunogen Region: |
296-346 aa |
| Specificity: |
This antibody detects endogenous levels of DIEXF at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human DIEXF at the amino acid range 296-346 |
| Post Translational Modifications | Phosphorylated. Phosphorylation is required to promote p53/TP53 degradation in the nucleolus which promotes cell cycle progression and liver development. |
| Function | Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53. |
| Protein Name | U3 Small Nucleolar Rna-Associated Protein 25 HomologDigestive Organ Expansion Factor HomologUtp25 Small Subunit Processor Component |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-U3 Small Nucleolar Rna-Associated Protein 25 Homolog antibodyAnti-Digestive Organ Expansion Factor Homolog antibodyAnti-Utp25 Small Subunit Processor Component antibodyAnti-UTP25 antibodyAnti-C1orf107 antibodyAnti-DEF antibodyAnti-DIEXF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
