| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 46 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | USP46 |
| Gene ID: | 64854 |
| Uniprot ID: | UBP46_HUMAN |
| Specificity: | UBP46 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 46Deubiquitinating Enzyme 46Ubiquitin Thioesterase 46Ubiquitin-Specific-Processing Protease 46 |
| Cellular Localisation | CytoplasmUsp46/Wdr48/Wdr20 Complex Is Predominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 46 antibodyAnti-Deubiquitinating Enzyme 46 antibodyAnti-Ubiquitin Thioesterase 46 antibodyAnti-Ubiquitin-Specific-Processing Protease 46 antibodyAnti-USP46 antibody |
Information sourced from Uniprot.org