Anti-USP45 antibody (301-350 aa) (STJ96207)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human USP45 at the amino acid range 301-350
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin carboxyl-terminal hydrolase 45 (301-350 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP45 |
| Gene ID | 85015 |
| Uniprot ID | UBP45_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human USP45 at the amino acid range 301-350 |
| Immunogen Region | 301-350 aa |
| Specificity | USP45 Polyclonal Antibody detects endogenous levels of USP45 protein. |
Additional Info
| Function | Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 45Deubiquitinating Enzyme 45Ubiquitin Thioesterase 45Ubiquitin-Specific-Processing Protease 45 |
| Database Links | Reactome: R-HSA-5696395 |
| Cellular Localisation | Photoreceptor Inner SegmentCytoplasmNucleus |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 45 antibodyAnti-Deubiquitinating Enzyme 45 antibodyAnti-Ubiquitin Thioesterase 45 antibodyAnti-Ubiquitin-Specific-Processing Protease 45 antibodyAnti-USP45 antibody |
Information sourced from Uniprot.org