| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 34 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
USP34 |
| Gene ID: |
9736 |
| Uniprot ID: |
UBP34_HUMAN |
| Specificity: |
This antibody detects endogenous levels of USP34 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human USP34 |
| Tissue Specificity | Expressed in brain at low level. |
| Function | Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 34Deubiquitinating Enzyme 34Ubiquitin Thioesterase 34Ubiquitin-Specific-Processing Protease 34 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-5689880 |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 34 antibodyAnti-Deubiquitinating Enzyme 34 antibodyAnti-Ubiquitin Thioesterase 34 antibodyAnti-Ubiquitin-Specific-Processing Protease 34 antibodyAnti-USP34 antibodyAnti-KIAA0570 antibodyAnti-KIAA0729 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
