| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | USP26 |
| Gene ID: | 83844 |
| Uniprot ID: | UBP26_HUMAN |
| Immunogen Region: | 664-913 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 664-913 of human USP26 (NP_114113.1). |
| Immunogen Sequence: | TSLCQFHKAGGKPASSPGTP LSKVDFQTVPENPKRKKYVK TSKFVAFDRIINPTKDLYED KNIRIPERFQKVSEQTQQCD GMRICEQAPQQALPQSFPKP GTQGHTKNLLRPTKLNLQKS NRNSLLALGSNKNPRNKDIL DKIKSKAKETKRNDDKGDHT YRLISVVSHLGKTLKSGHYI CDAYDFEKQIWFTYDDMRVL GIQEAQMQEDRRCTGYIFFY MHNEIFEEMLKREENAQLN |
| Tissue Specificity | Expressed in testis. |
| Function | Deubiquitinase regulating several biological processes through the deubiquitination of components of these processes. Involved in somatic cell reprogramming through the 'Lys-48'-linked deubiquitination and stabilization of CBX4 and CBX6, two components of the polycomb-repressive complex 1 (PRC1). Also deubiquitinates and probably stabilizes the androgen receptor (AR), regulating the androgen receptor signaling pathway. May play a role in spermatogenesis. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 26Deubiquitinating Enzyme 26Ubiquitin Thioesterase 26Ubiquitin-Specific-Processing Protease 26 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonFlagellum Axoneme |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 26 antibodyAnti-Deubiquitinating Enzyme 26 antibodyAnti-Ubiquitin Thioesterase 26 antibodyAnti-Ubiquitin-Specific-Processing Protease 26 antibodyAnti-USP26 antibody |
Information sourced from Uniprot.org