| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | USP24 |
| Gene ID: | 23358 |
| Uniprot ID: | UBP24_HUMAN |
| Immunogen Region: | 2431-2620 |
| Immunogen Sequence: | FTMLHFIKNQLETAPPHELK NTFQLLHEILVIEDPIQVER VKFVFETENGLLALMHHSNH VDSSRCYQCVKFLVTLAQKC PAAKEYFKENSHHWSWAVQW LQKKMSEHYWTPQSNVSNET STGKTFQRTISAQDTLAYAT ALLNEKEQSGSSNGSESSPA NENGDRHLQQGSESPMMIGE LRSDLDDVDP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 2431-2620 of human USP24 (NP_056121.2). |
| Function | Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 24Deubiquitinating Enzyme 24Ubiquitin Thioesterase 24Ubiquitin-Specific-Processing Protease 24 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 24 antibodyAnti-Deubiquitinating Enzyme 24 antibodyAnti-Ubiquitin Thioesterase 24 antibodyAnti-Ubiquitin-Specific-Processing Protease 24 antibodyAnti-USP24 antibodyAnti-KIAA1057 antibody |
Information sourced from Uniprot.org
