| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | USO1 |
| Gene ID: | 8615 |
| Uniprot ID: | USO1_HUMAN |
| Immunogen Region: | 663-962 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 663-962 of human USO1 (NP_003706.2). |
| Immunogen Sequence: | DLQLEELRQQVSTLKCQNEQ LQTAVTQQVSQIQQHKDQYN LLKIQLGKDNQHQGSYSEGA QMNGIQPEEIGRLREEIEEL KRNQELLQSQLTEKDSMIEN MKSSQTSGTNEQSSAIVSAR DSEQVAELKQELATLKSQLN SQSVEITKLQTEKQELLQKT EAFAKSVEVQGETETIIATK TTDVEGRLSALLQETKELKN EIKALSEERTAIKEQLDSSN STIAILQTEKDKLELEITD |
| Post Translational Modifications | Phosphorylated in a cell cycle-specific manner.phosphorylated in interphase but not in mitotic cells. Dephosphorylated protein associates with the Golgi membrane.phosphorylation promotes dissociation. |
| Function | General vesicular transport factor required for intercisternal transport in the Golgi stack.it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. |
| Protein Name | General Vesicular Transport Factor P115 Protein Uso1 Homolog Transcytosis-Associated Protein Tap Vesicle-Docking Protein |
| Database Links | Reactome: R-HSA-162658 Reactome: R-HSA-204005 Reactome: R-HSA-6807878 |
| Cellular Localisation | Cytoplasm Cytosol Golgi Apparatus Membrane Peripheral Membrane Protein Recycles Between The Cytosol And The Golgi Apparatus During Interphase During Interphase The Phosphorylated Form Is Found Exclusively In Cytosol The Unphosphorylated Form Is Associated With Golgi Apparatus Membranes |
| Alternative Antibody Names | Anti-General Vesicular Transport Factor P115 antibody Anti-Protein Uso1 Homolog antibody Anti-Transcytosis-Associated Protein antibody Anti-Tap antibody Anti-Vesicle-Docking Protein antibody Anti-USO1 antibody Anti-VDP antibody |
Information sourced from Uniprot.org