| Short Description : | Rabbit polyclonal anti-Uroporphyrinogen-III synthase (25-75 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Mgu |
| Gene ID: | 7390 |
| Uniprot ID: | HEM4_HUMAN |
| Immunogen: | Synthesized peptide derived from the human HEM4 at the amino acid range 25-75 |
| Immunogen Region: | 25-75 aa |
| Specificity: | This antibody detects endogenous levels of HEM4 at Human/Mouse |
| Function | Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). |
| Protein Name | Uroporphyrinogen-Iii SynthaseUroiiisUrosHydroxymethylbilane Hydrolyase CyclizingUroporphyrinogen-Iii Cosynthase |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Uroporphyrinogen-Iii Synthase antibodyAnti-Uroiiis antibodyAnti-Uros antibodyAnti-Hydroxymethylbilane Hydrolyase Cyclizing antibodyAnti-Uroporphyrinogen-Iii Cosynthase antibodyAnti-Mgu antibodyAnti-UROS antibody |
Information sourced from Uniprot.org
