Anti-Uroplakin antibody (114-173aa) [ZM204] (STJ180425)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk/IgG1k
ImmunogenRecombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein; recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B)
General Information
| Short Description | Mouse monoclonal Uroplakin (114-173aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZM204 |
| Isotype | IgG2bk/IgG1k |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2β8Β°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate labβstandardized diluent. Stability after dilution: 7 days at 24Β°C, 3 months at 2β8Β°C, 6months at β20Β°C. |
Target Information
| Gene Symbol | UPK1B |
| Gene ID | 7348 |
| Uniprot ID | UPK1B_HUMAN |
| Immunogen | Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein; recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) |
| Immunogen Region | 114-173aa |
| Specificity | Positive control: Bladder or urothelial carcinoma |
Additional Info
| Tissue Specificity | Bladder epithelium. |
| Post Translational Modifications | N-glycosylated with high-mannose oligosaccharides. |
| Function | Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. |
| Protein Name | Uroplakin-1bUp1bTetraspanin-20Tspan-20Uroplakin IbUpib |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Uroplakin-1b antibodyAnti-Up1b antibodyAnti-Tetraspanin-20 antibodyAnti-Tspan-20 antibodyAnti-Uroplakin Ib antibodyAnti-Upib antibodyAnti-UPK1B antibodyAnti-TSPAN20 antibody |
Information sourced from Uniprot.org