• Human bladder tissue was stained with Anti-Uroplakin III (ABT-UPK3) Antibody
  • Whole cell lysates were separated by 15% SDS-PAGE, and the membrane was blotted with anti-Uroplakin III (ABT-UPK3) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: mouse bladderPredicted band size: 30kDaObserved band size: 50-60kDaNon-specific band: 55kd, heavy chain of antibody in mouse bladder tissue

Anti-UPK3A antibody (200-287 aa) [ABT-UPK3] (STJ196797)

SKU:
STJ196797

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Uroplakin-3a (200-287 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT-UPK3
Conjugation: Unconjugated
Isotype: IgG1L
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: WB 500-2000
IHC-P 1:100-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UPK3A
Gene ID: 7380
Uniprot ID: UPK3A_HUMAN
Immunogen Region: 200-287 aa
Specificity: This antibody detects endogenous levels of human Uroplakin III. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
Immunogen: Synthesized peptide derived from the human Uroplakin III at the amino acid range 200-287
Function Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
Protein Name Uroplakin-3a
Up3a
Uroplakin Iii
Upiii
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Heterodimer Formation With Upk1b Is A Prerequisite To Exit Out Of The Endoplasmic Reticulum (Er)
Alternative Antibody Names Anti-Uroplakin-3a antibody
Anti-Up3a antibody
Anti-Uroplakin Iii antibody
Anti-Upiii antibody
Anti-UPK3A antibody
Anti-UPK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance