Anti-UNC45B antibody (STJA0008664)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human UNC45B
General Information
| Short Description | Rabbit polyclonal anti-Protein unc-45 homolog B for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UNC45B |
| Gene ID | 146862 |
| Uniprot ID | UN45B_HUMAN |
| Immunogen | Synthesized peptide derived from human UNC45B |
| Specificity | This antibody detects endogenous levels of UNC45B at Human, Mouse |
Additional Info
| Function | Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. |
| Protein Name | Protein Unc-45 Homolog BUnc-45bSmunc45 |
| Database Links | |
| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineA BandPerinuclear RegionCytosolExpressed At The Z Line And In The Perinuclear Region Of MyofibrilsTranslocates To The A Band In Response To Stress Conditions And Fibril Damage |
| Alternative Antibody Names | Anti-Protein Unc-45 Homolog B antibodyAnti-Unc-45b antibodyAnti-Smunc45 antibodyAnti-UNC45B antibodyAnti-CMYA4 antibodyAnti-UNC45 antibody |
Information sourced from Uniprot.org