| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
UNC45A |
| Gene ID: |
55898 |
| Uniprot ID: |
UN45A_HUMAN |
| Immunogen Region: |
1-200 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UNC45A (NP_061141.2). |
| Immunogen Sequence: |
MTVSGPGTPEPRPATPGASS VEQLRKEGNELFKCGDYGGA LAAYTQALGLDATPQDQAVL HRNRAACHLKLEDYDKAETE ASKAIEKDGGDVKALYRRSQ ALEKLGRLDQAVLDLQRCVS LEPKNKVFQEALRNIGGQIQ EKVRYMSSTDAKVEQMFQIL LDPEEKGTEKKQKASQNLVV LAREDAGAEKIFRSNGVQLL |
| Tissue Specificity | Detected in peripheral blood leukocytes, bone marrow, adrenal gland, trachea, spinal cord, thyroid, lymph node and stomach. |
| Function | Acts as a co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen. |
| Protein Name | Protein Unc-45 Homolog AUnc-45aGcunc-45Smooth Muscle Cell-Associated Protein 1Smap-1 |
| Cellular Localisation | CytoplasmPerinuclear RegionNucleusPredominant In The Perinuclear RegionLittle Protein In The Nucleus |
| Alternative Antibody Names | Anti-Protein Unc-45 Homolog A antibodyAnti-Unc-45a antibodyAnti-Gcunc-45 antibodyAnti-Smooth Muscle Cell-Associated Protein 1 antibodyAnti-Smap-1 antibodyAnti-UNC45A antibodyAnti-SMAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
