| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | UNC13C |
| Gene ID: | 440279 |
| Uniprot ID: | UN13C_HUMAN |
| Immunogen Region: | 1300-1400 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human UNC13C (NP_001074003.1). |
| Immunogen Sequence: | HFKKESDDFLGQTIVEVRTL SGEMDVWYNLEKRTDKSAVS GAIRLKINVEIKGEEKVAPY HIQYTCLHENLFHYLTEVKS NGGVKIPEVKGDEAWKVFFD D |
| Tissue Specificity | Exclusively expressed in brain. |
| Function | May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses. |
| Protein Name | Protein Unc-13 Homolog CMunc13-3 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinPresynaptic Cell MembraneLocalized To Presynaptic Structures |
| Alternative Antibody Names | Anti-Protein Unc-13 Homolog C antibodyAnti-Munc13-3 antibodyAnti-UNC13C antibody |
Information sourced from Uniprot.org