| Short Description : | Rabbit polyclonal UMPS (181-480) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UMPS |
| Gene ID: | 7372 |
| Uniprot ID: | UMPS_HUMAN |
| Immunogen Region: | 181-480 |
| Immunogen Sequence: | EILEQQKKVDAETVGRVKRF IQENVFVAANHNGSPLSIKE APKELSFGARAELPRIHPVA SKLLRLMQKKETNLCLSADV SLARELLQLADALGPSICML KTHVDILNDFTLDVMKELIT LAKCHEFLIFEDRKFADIGN TVKKQYEGGIFKIASWADLV NAHVVPGSGVVKGLQEVGLP LHRGCLLIAEMSSTGSLATG DYTRAAVRMAEEHSEFVVGF ISGSRVSMKPEFLHLTPGV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human UMPS (NP_000364.1). |
| Function | Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP). |
| Protein Name | Uridine 5'-Monophosphate SynthaseUmp Synthase Includes - Orotate PhosphoribosyltransferaseOprtOprtase - Orotidine 5'-Phosphate DecarboxylaseOdcOmpdOmpdecase |
| Database Links | Reactome: R-HSA-500753 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Uridine 5'-Monophosphate Synthase antibodyAnti-Ump Synthase Includes - Orotate Phosphoribosyltransferase antibodyAnti-Oprt antibodyAnti-Oprtase - Orotidine 5'-Phosphate Decarboxylase antibodyAnti-Odc antibodyAnti-Ompd antibodyAnti-Ompdecase antibodyAnti-UMPS antibodyAnti-OK antibodyAnti-SW-cl.21 antibody |
Information sourced from Uniprot.org
