• Western blot analysis of extracts of Jurkat cells, using UMPS antibody (STJ27445) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-UMPS antibody (181-480) (STJ27445)

SKU:
STJ27445

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-UMPS (181-480) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UMPS
Gene ID: 7372
Uniprot ID: UMPS_HUMAN
Immunogen Region: 181-480
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human UMPS (NP_000364.1).
Immunogen Sequence: EILEQQKKVDAETVGRVKRF IQENVFVAANHNGSPLSIKE APKELSFGARAELPRIHPVA SKLLRLMQKKETNLCLSADV SLARELLQLADALGPSICML KTHVDILNDFTLDVMKELIT LAKCHEFLIFEDRKFADIGN TVKKQYEGGIFKIASWADLV NAHVVPGSGVVKGLQEVGLP LHRGCLLIAEMSSTGSLATG DYTRAAVRMAEEHSEFVVGF ISGSRVSMKPEFLHLTPGV
Function Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP).
Protein Name Uridine 5'-Monophosphate Synthase
Ump Synthase Includes - Orotate Phosphoribosyltransferase
Oprt
Oprtase - Orotidine 5'-Phosphate Decarboxylase
Odc
Ompd
Ompdecase
Database Links Reactome: R-HSA-500753
Alternative Antibody Names Anti-Uridine 5'-Monophosphate Synthase antibody
Anti-Ump Synthase Includes - Orotate Phosphoribosyltransferase antibody
Anti-Oprt antibody
Anti-Oprtase - Orotidine 5'-Phosphate Decarboxylase antibody
Anti-Odc antibody
Anti-Ompd antibody
Anti-Ompdecase antibody
Anti-UMPS antibody
Anti-OK antibody
Anti-SW-cl.21 antibody

Information sourced from Uniprot.org

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