Anti-UFC1 antibody (1-130) [S4205RM] (STJ11104205)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Ubiquitin-Fold Modifier-Conjugating Enzyme 1 (1-130) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4205RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UFC1 |
| Gene ID | 51506 |
| Uniprot ID | UFC1_HUMAN |
| Immunogen Region | 1-130 |
| Immunogen Sequence | MADEATRRVVSEIPVLKTNA GPRDRELWVQRLKEEYQSLI RYVENNKNADNDWFRLESNK EGTRWFGKCWYIHDLLKYEF DIEFDIPITYPTTAPEIAVP ELDGKTAKMYRGGKICLTDH FKPLWARNVP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of Human UFC1 (NP_057490.2). |
Additional Info
| Post Translational Modifications | Ufmylated at Lys-122. Deufmylated by UFSP1. |
| Function | E2-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy). |
| Protein Name | Ubiquitin-Fold Modifier-Conjugating Enzyme 1Ufm1-Conjugating Enzyme 1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin-Fold Modifier-Conjugating Enzyme 1 antibodyAnti-Ufm1-Conjugating Enzyme 1 antibodyAnti-UFC1 antibodyAnti-CGI-126 antibodyAnti-HSPC155 antibody |
Information sourced from Uniprot.org