| Tissue Specificity | Enhanced expression in testis. |
| Function | May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. |
| Protein Name | Ubx Domain-Containing Protein 6Ubx Domain-Containing Protein 1 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinNucleusCytoskeletonMicrotubule Organizing CenterCentrosomeEarly Endosome MembraneLate Endosome MembraneLysosome MembraneLocalizes At The Centrosome Both In Interphase And During MitosisMay Be Recruited To Endosomal And Lysosomal Membranes As Part Of A Ternary Complex With Cav1 And VcpRecruited To Damaged Lysosomes Decorated With K48-Linked Ubiquitin Chains |
| Alternative Antibody Names | Anti-Ubx Domain-Containing Protein 6 antibodyAnti-Ubx Domain-Containing Protein 1 antibodyAnti-UBXN6 antibodyAnti-UBXD1 antibodyAnti-UBXDC2 antibody |
Information sourced from Uniprot.org
