| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nucleolar transcription factor 1 (420-500 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBTF |
| Gene ID: | 7343 |
| Uniprot ID: | UBF1_HUMAN |
| Immunogen Region: | 420-500 aa |
| Specificity: | UBF Polyclonal Antibody detects endogenous levels of UBF protein. |
| Immunogen: | Synthesized peptide derived from UBF at the amino acid range 420-500 |
| Function | Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I (Pol I) through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element and can activate Pol I promoter escape. |
| Protein Name | Nucleolar Transcription Factor 1Autoantigen Nor-90Upstream-Binding Factor 1Ubf-1 |
| Database Links | Reactome: R-HSA-427413Reactome: R-HSA-73728Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Nucleolar Transcription Factor 1 antibodyAnti-Autoantigen Nor-90 antibodyAnti-Upstream-Binding Factor 1 antibodyAnti-Ubf-1 antibodyAnti-UBTF antibodyAnti-UBF antibodyAnti-UBF1 antibody |
Information sourced from Uniprot.org
