Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-UBTF (200-440) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
UBTF |
Gene ID: |
7343 |
Uniprot ID: |
UBF1_HUMAN |
Immunogen Region: |
200-440 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-440 of human UBTF (NP_055048.1). |
Immunogen Sequence: |
KTPQQLWYTHEKKVYLKVRP DATTKEVKDSLGKQWSQLSD KKRLKWIHKALEQRKEYEEI MRDYIQKHPELNISEEGITK STLTKAERQLKDKFDGRPTK PPPNSYSLYCAELMANMKDV PSTERMVLCSQQWKLLSQKE KDAYHKKCDQKKKDYEVELL RFLESLPEEEQQRVLGEEKM LNINKKQATSPASKKPAQEG GKGGSEKPKRPVSAMFIFSE EKRRQLQEERPELSESELT |
Post Translational Modifications | Phosphorylated and activated by PIK3CA. |
Function | Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. |
Protein Name | Nucleolar Transcription Factor 1Autoantigen Nor-90Upstream-Binding Factor 1Ubf-1 |
Database Links | Reactome: R-HSA-427413Reactome: R-HSA-73728Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
Cellular Localisation | NucleusNucleolus |
Alternative Antibody Names | Anti-Nucleolar Transcription Factor 1 antibodyAnti-Autoantigen Nor-90 antibodyAnti-Upstream-Binding Factor 1 antibodyAnti-Ubf-1 antibodyAnti-UBTF antibodyAnti-UBF antibodyAnti-UBF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance