| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBL5 |
| Gene ID: | 59286 |
| Uniprot ID: | UBL5_HUMAN |
| Immunogen Region: | 1-73 |
| Immunogen Sequence: | MIEVVCNDRLGKKVRVKCNT DDTIGDLKKLIAAQTGTRWN KIVLKKWYTIFKDHVSLGDY EIHDGMNLELYYQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-73 of human UBL5 (NP_077268.1). |
| Tissue Specificity | Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and lymphoblasts. |
| Function | Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins. Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers. Also plays a protective role against ER stress-induced apoptosis. |
| Protein Name | Ubiquitin-Like Protein 5 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusCajal Body |
| Alternative Antibody Names | Anti-Ubiquitin-Like Protein 5 antibodyAnti-UBL5 antibody |
Information sourced from Uniprot.org
