| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBE2L6 |
| Gene ID: | 9246 |
| Uniprot ID: | UB2L6_HUMAN |
| Immunogen Region: | 100-153 |
| Immunogen Sequence: | KTCQVLEALNVLVNRPNIRE PLRMDLADLLTQNPELFRKN AEEFTLRFGVDRPS |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-153 of human UBE2L6 (NP_004214.1). |
| Tissue Specificity | Present in natural killer cells (at protein level). |
| Post Translational Modifications | ISGylated. |
| Function | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. |
| Protein Name | Ubiquitin/Isg15-Conjugating Enzyme E2 L6E2 Ubiquitin-Conjugating Enzyme L6Retinoic Acid-Induced Gene B ProteinRig-BUbch8Ubiquitin Carrier Protein L6Ubiquitin-Protein Ligase L6 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-168928Reactome: R-HSA-5656169Reactome: R-HSA-936440Reactome: R-HSA-977225Reactome: R-HSA-983168Reactome: R-HSA-9833110Reactome: R-HSA-9833482Reactome: R-HSA-9909505 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin/Isg15-Conjugating Enzyme E2 L6 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme L6 antibodyAnti-Retinoic Acid-Induced Gene B Protein antibodyAnti-Rig-B antibodyAnti-Ubch8 antibodyAnti-Ubiquitin Carrier Protein L6 antibodyAnti-Ubiquitin-Protein Ligase L6 antibodyAnti-UBE2L6 antibodyAnti-UBCH8 antibody |
Information sourced from Uniprot.org
