Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | UBE2G2 |
Gene ID: | 7327 |
Uniprot ID: | UB2G2_HUMAN |
Immunogen Region: | 1-165 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human UBE2G2 (NP_003334.2). |
Immunogen Sequence: | MAGTALKRLMAEYKQLTLNP PEGIVAGPMNEENFFEWEAL IMGPEDTCFEFGVFPAILSF PLDYPLSPPKMRFTCEMFHP NIYPDGRVCISILHAPGDDP MGYESSAERWSPVQSVEKIL LSVVSMLAEPNDESGANVDA SKMWRDDREQFYKIAKQIVQ KSLGL |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation. |
Protein Name | Ubiquitin-Conjugating Enzyme E2 G2E2 Ubiquitin-Conjugating Enzyme G2Ubiquitin Carrier Protein G2Ubiquitin-Protein Ligase G2 |
Database Links | Reactome: R-HSA-8866652Reactome: R-HSA-983168 |
Cellular Localisation | Endoplasmic ReticulumLipid Droplet |
Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 G2 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme G2 antibodyAnti-Ubiquitin Carrier Protein G2 antibodyAnti-Ubiquitin-Protein Ligase G2 antibodyAnti-UBE2G2 antibodyAnti-UBC7 antibody |
Information sourced from Uniprot.org