Anti-UBE2G2 antibody (1-165) (STJ112443)

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STJ112443
£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UBE2G2
Gene ID: 7327
Uniprot ID: UB2G2_HUMAN
Immunogen Region: 1-165
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human UBE2G2 (NP_003334.2).
Immunogen Sequence: MAGTALKRLMAEYKQLTLNP PEGIVAGPMNEENFFEWEAL IMGPEDTCFEFGVFPAILSF PLDYPLSPPKMRFTCEMFHP NIYPDGRVCISILHAPGDDP MGYESSAERWSPVQSVEKIL LSVVSMLAEPNDESGANVDA SKMWRDDREQFYKIAKQIVQ KSLGL
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation.
Protein Name Ubiquitin-Conjugating Enzyme E2 G2
E2 Ubiquitin-Conjugating Enzyme G2
Ubiquitin Carrier Protein G2
Ubiquitin-Protein Ligase G2
Database Links Reactome: R-HSA-8866652
Reactome: R-HSA-983168
Cellular Localisation Endoplasmic Reticulum
Lipid Droplet
Alternative Antibody Names Anti-Ubiquitin-Conjugating Enzyme E2 G2 antibody
Anti-E2 Ubiquitin-Conjugating Enzyme G2 antibody
Anti-Ubiquitin Carrier Protein G2 antibody
Anti-Ubiquitin-Protein Ligase G2 antibody
Anti-UBE2G2 antibody
Anti-UBC7 antibody

Information sourced from Uniprot.org