• Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
  • Western blot analysis of extracts from Jurkat cells, using UBE2A/B Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-UBE2A/B antibody (C-Term) (STJ96446)

SKU:
STJ96446

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ubiquitin-conjugating enzyme E2 A and Ubiquitin-conjugating enzyme E2 B (C-Term) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UBE2A
UBE2B
Gene ID: 7319
7320
Uniprot ID: UBE2A_HUMAN
UBE2B_HUMAN
Immunogen Region: C-Term
Specificity: UBE2A/B Polyclonal Antibody detects endogenous levels of UBE2A/B protein.
Immunogen: Synthesized peptide derived from the C-terminal region of human UBE2A/B.
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Protein Name Ubiquitin-Conjugating Enzyme E2 A
E2 Ubiquitin-Conjugating Enzyme A
Rad6 Homolog A
Hr6a
Hhr6a
Ubiquitin Carrier Protein A
Ubiquitin-Protein Ligase A
Database Links Reactome: R-HSA-8866652
Reactome: R-HSA-8866654
Reactome: R-HSA-983168
Alternative Antibody Names Anti-Ubiquitin-Conjugating Enzyme E2 A antibody
Anti-E2 Ubiquitin-Conjugating Enzyme A antibody
Anti-Rad6 Homolog A antibody
Anti-Hr6a antibody
Anti-Hhr6a antibody
Anti-Ubiquitin Carrier Protein A antibody
Anti-Ubiquitin-Protein Ligase A antibody
Anti-UBE2A antibody
Anti-RAD6A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance