Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Ubiquitin-associated domain-containing protein 1 (91-140 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
UBAC1 |
Gene ID: |
10422 |
Uniprot ID: |
UBAC1_HUMAN |
Immunogen Region: |
91-140 aa |
Specificity: |
GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human UBAC1 at the amino acid range 91-140 |
Function | Non-catalytic component of the KPC complex, a E3 ubiquitin-protein ligase complex that mediates polyubiquitination of target proteins, such as CDKN1B and NFKB1. The KPC complex catalyzes polyubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. The KPC complex also acts as a key regulator of the NF-kappa-B signaling by promoting maturation of the NFKB1 component of NF-kappa-B by catalyzing ubiquitination of the NFKB1 p105 precursor. Within the KPC complex, UBAC1 acts as an adapter that promotes the transfer of target proteins that have been polyubiquitinated by RNF123/KPC1 to the 26S proteasome. |
Protein Name | Ubiquitin-Associated Domain-Containing Protein 1Uba Domain-Containing Protein 1Glialblastoma Cell Differentiation-Related Protein 1Kip1 Ubiquitination-Promoting Complex Protein 2 |
Database Links | Reactome: R-HSA-983168 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Ubiquitin-Associated Domain-Containing Protein 1 antibodyAnti-Uba Domain-Containing Protein 1 antibodyAnti-Glialblastoma Cell Differentiation-Related Protein 1 antibodyAnti-Kip1 Ubiquitination-Promoting Complex Protein 2 antibodyAnti-UBAC1 antibodyAnti-GBDR1 antibodyAnti-KPC2 antibodyAnti-UBADC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance