• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using UBE1L Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HeLa cells, using UBE1L Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using UBE1L Polyclonal Antibody diluted at 1：2000. Secondary antibody was diluted at 1:20000

Anti-UBA7 antibody (963-1012 aa) (STJ96162)

SKU:
STJ96162

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ubiquitin-like modifier-activating enzyme 7 (963-1012 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UBA7
Gene ID: 7318
Uniprot ID: UBA7_HUMAN
Immunogen Region: 963-1012 aa
Specificity: UBE1L Polyclonal Antibody detects endogenous levels of UBE1L protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human UBE1L at the amino acid range 963-1012
Post Translational Modifications ISGylated. Ubiquitinated by RNF170.
Function E1-activating enzyme that catalyzes the covalent conjugation of the ubiquitin-like protein product of ISG15 to additional interferon stimulated proteins (ISGs) as well as other cellular proteins such as P53 in a process termed protein ISGylation. Plays an essential role in antiviral immunity together with ISG15 by restricting the replication of many viruses including rabies virus, influenza virus, sindbis virus, rotavirus or human cytomegalovirus. For example, ISG15 modification of influenza A protein NS1 disrupts the association of the NS1 with importin-alpha leading to NS1 nuclear import inhibition. ISGylation of human cytomegalovirs protein UL26 regulates its stability and inhibits its activities to suppress NF-kappa-B signaling.
Protein Name Ubiquitin-Like Modifier-Activating Enzyme 7
Ubiquitin-Activating Enzyme 7
D8
Ubiquitin-Activating Enzyme E1 Homolog
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-168928
Reactome: R-HSA-5656169
Reactome: R-HSA-936440
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Ubiquitin-Like Modifier-Activating Enzyme 7 antibody
Anti-Ubiquitin-Activating Enzyme 7 antibody
Anti-D8 antibody
Anti-Ubiquitin-Activating Enzyme E1 Homolog antibody
Anti-UBA7 antibody
Anti-UBE1L antibody
Anti-UBE2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance