Anti-UBA6 antibody (STJ191587)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin-like modifier-activating enzyme 6 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBA6 |
| Gene ID | 55236 |
| Uniprot ID | UBA6_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | UBA6 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Also activates UBD/FAT10 conjugation via adenylation of its C-terminal glycine. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility. |
| Protein Name | Ubiquitin-Like Modifier-Activating Enzyme 6Ubiquitin-Activating Enzyme 6Monocyte Protein 4Mop-4Ubiquitin-Activating Enzyme E1-Like Protein 2E1-L2 |
| Database Links | Reactome: R-HSA-8866652Reactome: R-HSA-983168 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin-Like Modifier-Activating Enzyme 6 antibodyAnti-Ubiquitin-Activating Enzyme 6 antibodyAnti-Monocyte Protein 4 antibodyAnti-Mop-4 antibodyAnti-Ubiquitin-Activating Enzyme E1-Like Protein 2 antibodyAnti-E1-L2 antibodyAnti-UBA6 antibodyAnti-MOP4 antibodyAnti-UBE1L2 antibody |
Information sourced from Uniprot.org