| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-5, 6-dihydroxyindole-2-carboxylic acid oxidase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TYRP1 |
| Gene ID: |
7306 |
| Uniprot ID: |
TYRP1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of TRP1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human TRP1 |
| Post Translational Modifications | Glycosylated. |
| Function | Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. |
| Protein Name | 5 -6-Dihydroxyindole-2-Carboxylic Acid OxidaseDhica OxidaseCatalase BGlycoprotein 75Melanoma Antigen Gp75Tyrosinase-Related Protein 1TrpTrp-1Trp1 |
| Database Links | Reactome: R-HSA-5662702 |
| Cellular Localisation | Melanosome MembraneSingle-Pass Type I Membrane ProteinLocated To Mature Stage Iii And Iv Melanosomes And Apposed Endosomal Tubular MembranesTransported To Pigmented Melanosomes By The Bloc-1 ComplexProper Trafficking To Melanosome Is Regulated By Sgsm2Ankrd27Rab9aRab32 And Rab38 |
| Alternative Antibody Names | Anti-5 -6-Dihydroxyindole-2-Carboxylic Acid Oxidase antibodyAnti-Dhica Oxidase antibodyAnti-Catalase B antibodyAnti-Glycoprotein 75 antibodyAnti-Melanoma Antigen Gp75 antibodyAnti-Tyrosinase-Related Protein 1 antibodyAnti-Trp antibodyAnti-Trp-1 antibodyAnti-Trp1 antibodyAnti-TYRP1 antibodyAnti-CAS2 antibodyAnti-TYRP antibodyAnti-TYRRP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
