Anti-TYRP1 antibody (STJA0009785)

SKU:
STJA0009785
£49.00 - £261.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Rabbit polyclonal anti-5, 6-dihydroxyindole-2-carboxylic acid oxidase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:TYRP1
Gene ID:7306
Uniprot ID:TYRP1_HUMAN
Immunogen:Synthesized peptide derived from human TRP1
Specificity:This antibody detects endogenous levels of TRP1 at Human, Mouse
Post Translational Modifications Glycosylated.
Function Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.
Protein Name 5 -6-Dihydroxyindole-2-Carboxylic Acid Oxidase
Dhica Oxidase
Catalase B
Glycoprotein 75
Melanoma Antigen Gp75
Tyrosinase-Related Protein 1
Trp
Trp-1
Trp1
Database Links Reactome: R-HSA-5662702
Reactome: R-HSA-9824585
Cellular Localisation Melanosome Membrane
Single-Pass Type I Membrane Protein
Located To Mature Stage Iii And Iv Melanosomes And Apposed Endosomal Tubular Membranes
Transported To Pigmented Melanosomes By The Bloc-1 Complex
Proper Trafficking To Melanosome Is Regulated By Sgsm2
Ankrd27
Rab9a
Rab32 And Rab38
Alternative Antibody Names Anti-5 -6-Dihydroxyindole-2-Carboxylic Acid Oxidase antibody
Anti-Dhica Oxidase antibody
Anti-Catalase B antibody
Anti-Glycoprotein 75 antibody
Anti-Melanoma Antigen Gp75 antibody
Anti-Tyrosinase-Related Protein 1 antibody
Anti-Trp antibody
Anti-Trp-1 antibody
Anti-Trp1 antibody
Anti-TYRP1 antibody
Anti-CAS2 antibody
Anti-TYRP antibody
Anti-TYRRP antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0019064 Anti-TYRP1 antibody [TA99] (STJA0019064) Mouse Monoclonal Human/Mouse/Rat IF/WB
STJA0024034 Anti-Recombinant-TYRP1 antibody [RM1Q50] (STJA0024034) Rabbit Monoclonal Human IHC/IP/WB
STJP015089 Human TYRP1 protein (Recombinant) (C-His) (STJP015089) Mammalian cells ELISA/Immunogen/SDS-PAGE/WB
STJP013222 Human TYRP1 protein (Recombinant) (C-His) (STJP013222) Mammalian cells ELISA/WB
STJP014433 Human TYRP1 protein (Recombinant) (C-His) (STJP014433) E.coli ELISA/WB

Related Products

!