• Anti-Tyrosinase antibody [T311] (STJ16101798)

Anti-Tyrosinase antibody [T311] (STJ16101798)

SKU:
STJ16101798-1

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Tyrosinase is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: T311
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Tissue culture supernatant with sodium azide
Concentration: >=89 mg/L
Dilution Range: IHC-P 1:50
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: TYR
Gene ID: 7299
Uniprot ID: TYRO_HUMAN
Immunogen: Recombinant prokaryotic protein corresponding to the tyrosinase molecule.
Post Translational Modifications Glycosylated.
Function This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Protein Name Tyrosinase
Lb24-Ab
Monophenol Monooxygenase
Sk29-Ab
Tumor Rejection Antigen Ab
Database Links Reactome: R-HSA-5662702
Cellular Localisation Melanosome Membrane
Single-Pass Type I Membrane Protein
Melanosome
Proper Trafficking To Melanosome Is Regulated By Sgsm2
Ankrd27
Rab9a
Rab32 And Rab38
Alternative Antibody Names Anti-Tyrosinase antibody
Anti-Lb24-Ab antibody
Anti-Monophenol Monooxygenase antibody
Anti-Sk29-Ab antibody
Anti-Tumor Rejection Antigen Ab antibody
Anti-TYR antibody

Information sourced from Uniprot.org

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