![Western blot analysis of lysates from wild type (WT) and TXNDC5 knockout (KO) 293T cells, using [KO Validated] TXNDC5 Rabbit polyclonal antibody (STJ11100807) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/89743/358218/STJ11100807_1__82919.1713122544.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXNDC5 knockout (KO) 293T cells, using [KO Validated] TXNDC5 Rabbit polyclonal antibody (STJ11100807) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
![Western blot analysis of lysates from wild type (WT) and TXNDC5 knockout (KO) 293T cells, using [KO Validated] TXNDC5 Rabbit polyclonal antibody (STJ11100807) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/89743/358218/STJ11100807_1__82919.1713122544.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXNDC5 knockout (KO) 293T cells, using [KO Validated] TXNDC5 Rabbit polyclonal antibody (STJ11100807) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TXNDC5 |
| Gene ID: | 81567 |
| Uniprot ID: | TXND5_HUMAN |
| Immunogen Region: | 1-324 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-324 of human TXNDC5 (NP_001139021.1). |
| Immunogen Sequence: | MEDAKVYVAKVDCTAHSDVC SAQGVRGYPTLKLFKPGQEA VKYQGPRDFQTLENWMLQTL NEEPVTPEPEVEPPSAPELK QGLYELSASNFELHVAQGDH FIKFFAPWCGHCKALAPTWE QLALGLEHSETVKIGKVDCT QHYELCSGNQVRGYPTLLWF RDGKKVDQYKGKRDLESLRE YVESQLQRTETGATETVTPS EAPVLAAEPEADKGTVLALT ENNFDDTIAEGITFIKFYA |
| Function | Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds. |
| Protein Name | Thioredoxin Domain-Containing Protein 5Endoplasmic Reticulum Resident Protein 46Er Protein 46Erp46Thioredoxin-Like Protein P46 |
| Database Links | Reactome: R-HSA-432720Reactome: R-HSA-432722Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Thioredoxin Domain-Containing Protein 5 antibodyAnti-Endoplasmic Reticulum Resident Protein 46 antibodyAnti-Er Protein 46 antibodyAnti-Erp46 antibodyAnti-Thioredoxin-Like Protein P46 antibodyAnti-TXNDC5 antibodyAnti-TLP46 antibodyAnti-UNQ364 antibodyAnti-PRO700 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TXNDC5 knockout (KO) 293T cells, using [KO Validated] TXNDC5 Rabbit polyclonal antibody (STJ11100806) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89742/358217/STJ11100806_1__90465.1713122542.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXNDC5 knockout (KO) 293T cells, using [KO Validated] TXNDC5 Rabbit polyclonal antibody (STJ11100806) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
