| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-TXNDC11 (113-126) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 100kDa band observed in Human Spleen and Thymus lysates (calculated MW of 108kDa according to NP_056998.4). Recommended concentration: 1-3µg/ml. Primary incubation was 1 hour. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TXNDC11 |
| Gene ID: | 51061 |
| Uniprot ID: | TXD11_HUMAN |
| Immunogen Region: | 113-126 |
| Accession Number: | NP_056998.4 |
| Immunogen Sequence: | QLDYAEYVRRDSE |
| Function | May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. |
| Protein Name | Thioredoxin Domain-Containing Protein 11Ef-Hand-Binding Protein 1 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Thioredoxin Domain-Containing Protein 11 antibodyAnti-Ef-Hand-Binding Protein 1 antibodyAnti-TXNDC11 antibodyAnti-EFP1 antibody |
Information sourced from Uniprot.org
