• Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:400 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:400 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:400 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Western blot analysis of 1, mouse-liver 2, hela cells using primary antibody diluted at 1:1000 (4°C overnight). Secondary antibody：Goat Anti-rabbit IgG IRDye 800 ( diluted at 1:5000, 25°C, 1 hour)

Anti-TXN antibody (52-101 aa) (STJ98852)

SKU:
STJ98852

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Thioredoxin (52-101 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 100-300
WB 1:500-2000
ELISA 1:10000-20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TXN
Gene ID: 7295
Uniprot ID: THIO_HUMAN
Immunogen Region: 52-101 aa
Specificity: This antibody detects endogenous levels of Thioredoxin
Immunogen: Synthesized peptide derived from the human Thioredoxin at the amino acid range 52-101
Function Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
Protein Name Thioredoxin
Trx
Atl-Derived Factor
Adf
Surface-Associated Sulphydryl Protein
Sasp
Allergen Hom S Trx
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-3299685
Reactome: R-HSA-499943
Reactome: R-HSA-5628897
Reactome: R-HSA-5676934
Reactome: R-HSA-844456
Reactome: R-HSA-9617629
Reactome: R-HSA-9660826
Cellular Localisation Nucleus
Cytoplasm
Secreted
Translocates From The Cytoplasm Into The Nucleus After Phorbol 12-Myristate 13-Acetate Induction (Pma)
Predominantly In The Cytoplasm In Non Irradiated Cells
Radiation Induces Translocation Of Trx From The Cytoplasm To The Nucleus
Secreted By A Leaderless Secretory Pathway
Alternative Antibody Names Anti-Thioredoxin antibody
Anti-Trx antibody
Anti-Atl-Derived Factor antibody
Anti-Adf antibody
Anti-Surface-Associated Sulphydryl Protein antibody
Anti-Sasp antibody
Anti-Allergen Hom S Trx antibody
Anti-TXN antibody
Anti-TRDX antibody
Anti-TRX antibody
Anti-TRX1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance