Anti-TUFM antibody (325-375) {Biotin} (STJ506048)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 325-375 on human Elongation factor Tu, mitochondrial.
General Information
| Short Description | Rabbit polyclonal antibody anti-TUFM (325-375) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.5-1.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:50, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TUFM |
| Gene ID | 7284 |
| Uniprot ID | EFTU_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 325-375 on human Elongation factor Tu, mitochondrial. |
| Immunogen Region | 325-375 |
Additional Info
| Function | Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. |
| Protein Name | Elongation Factor Tu - MitochondrialEf-TuP43 |
| Database Links | Reactome: R-HSA-5389840Reactome: R-HSA-9754560 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Elongation Factor Tu - Mitochondrial antibodyAnti-Ef-Tu antibodyAnti-P43 antibodyAnti-TUFM antibody |
Information sourced from Uniprot.org