| Host: | Rabbit |
| Applications: | WB/ICC/IF/IP |
| Reactivity: | Human/Mouse/Rat/Hamster |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-gamma Tubulin (231-451 aa) is suitable for use in Western Blot, Immunocytochemistry, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | R06-6A6 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/ml |
| Dilution Range: | WB 1:500-1:1000 IF 1:50-1:200 IP 1:20 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TUBG1 |
| Gene ID: | 7283 |
| Uniprot ID: | TBG1_HUMAN |
| Immunogen Region: | 231-451 aa |
| Immunogen: | Recombinant protein of human gamma Tubulin |
| Post Translational Modifications | Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome. |
| Function | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. |
| Protein Name | Tubulin Gamma-1 Chain Gamma-1-Tubulin Gamma-Tubulin Complex Component 1 Gcp-1 |
| Database Links | Reactome: R-HSA-2565942 Reactome: R-HSA-380259 Reactome: R-HSA-380270 Reactome: R-HSA-380284 Reactome: R-HSA-380320 Reactome: R-HSA-5620912 Reactome: R-HSA-8854518 |
| Cellular Localisation | Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Spindle Localizes To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Tubulin Gamma-1 Chain antibody Anti-Gamma-1-Tubulin antibody Anti-Gamma-Tubulin Complex Component 1 antibody Anti-Gcp-1 antibody Anti-TUBG1 antibody Anti-TUBG antibody |
Information sourced from Uniprot.org