| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Chicken/Human/Mouse/Rat/Xenopus |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Alpha 6-Tubulin (central Region) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000IHCICCIP |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TUBA1C |
| Gene ID: | 84790 |
| Uniprot ID: | TBA1C_HUMAN |
| Immunogen Region: | central Region |
| Specificity: | The antibody detects a 50 kDa* protein corresponding to the molecular mass of Alpha-Tubulin on SDS-PAGE immunoblots of human smooth muscle cells (A7r5) and mouse brain, as well as human recombinant a1-tubulin. |
| Immunogen: | Alpha 6-Tubulin synthetic peptide (coupled to KLH) corresponds to amino acid residues from the central region of human Alpha 6-Tubulin. This sequence is well conserved in most Alpha-tubulin isoforms from most eukaryotic species, but is not conserved |
| Function | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. |
| Protein Name | Tubulin Alpha-1c ChainAlpha-Tubulin 6Tubulin Alpha-6 Chain Cleaved Into - Detyrosinated Tubulin Alpha-1c Chain |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-190840Reactome: R-HSA-190861Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-3371497Reactome: R-HSA-380320Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-389977Reactome: R-HSA-437239Reactome: R-HSA-5610787Reactome: R-HSA-5617833Reactome: R-HSA-5620924Reactome: R-HSA-5626467Reactome: R-HSA-5663220Reactome: R-HSA-6807878Reactome: R-HSA-6811434Reactome: R-HSA-6811436Reactome: R-HSA-68877Reactome: R-HSA-8852276Reactome: R-HSA-8955332Reactome: R-HSA-9609690Reactome: R-HSA-9609736Reactome: R-HSA-9619483Reactome: R-HSA-9646399Reactome: R-HSA-9648025Reactome: R-HSA-9668328Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Tubulin Alpha-1c Chain antibodyAnti-Alpha-Tubulin 6 antibodyAnti-Tubulin Alpha-6 Chain Cleaved Into - Detyrosinated Tubulin Alpha-1c Chain antibodyAnti-TUBA1C antibodyAnti-TUBA6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance