Anti-TUB1 antibody [R57-1T-4] (STJA0035537)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human TUB1
General Information
| Short Description | Rabbit monoclonal anti-TUB1 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R57-1T-4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TUB |
| Gene ID | 7275 |
| Uniprot ID | TUB_HUMAN |
| Immunogen | A synthesized peptide derived from human TUB1 |
Additional Info
| Function | Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight. Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. |
| Protein Name | Tubby Protein Homolog |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusSecretedCell MembranePeripheral Membrane ProteinCytoplasmic SideBinds Phospholipid And Is Anchored To The Plasma Membrane Through Binding Phosphatidylinositol 45-BisphosphateIs Released Upon Activation Of Phospholipase CTranslocates From The Plasma Membrane To The Nucleus Upon Activation Of Guanine Nucleotide-Binding Protein G(Q) Subunit AlphaDoes Not Have A Cleavable Signal Peptide And Is Secreted By A Non-Conventional Pathway |
| Alternative Antibody Names | Anti-Tubby Protein Homolog antibodyAnti-TUB antibody |
Information sourced from Uniprot.org