| Short Description : | Goat polyclonal antibody anti-TSPO/PBR-Isoform (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications. |
| Applications: | Pep-ELISA/WB/IHC/IF/FC |
| Host: | Goat |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 17kDa band observed in Human Breast cancer lysates and approx 16kDa in Human Ovary and Skin lysates, and in lysates of cell line A431 (calculated MW of 18.8kDa according to NP_ |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TSPO |
| Gene ID: | 706 |
| Uniprot ID: | TSPO_HUMAN |
| Accession Number: | NP_000705.2 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | RDNHGWRGGRRLPE |
| Specificity: | This antibody is expected to recognise one isoform (NP_000705.2) only. |
| Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
| Protein Name | Translocator ProteinMitochondrial Benzodiazepine ReceptorPkbsPeripheral-Type Benzodiazepine ReceptorPbr |
| Database Links | Reactome: R-HSA-196108 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Translocator Protein antibodyAnti-Mitochondrial Benzodiazepine Receptor antibodyAnti-Pkbs antibodyAnti-Peripheral-Type Benzodiazepine Receptor antibodyAnti-Pbr antibodyAnti-TSPO antibodyAnti-BZRP antibodyAnti-MBR antibody |
Information sourced from Uniprot.org
