• STJ70985 (0. 3µg/ml) staining of A431 cell lysate. (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ70985 Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
  • STJ70985 Immunofluorescence analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
  • STJ70985 Flow cytometric analysis of paraformaldehyde fixed MCF7 cells (blue line) , permeabilized with 0. 5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Anti-TSPO/PBR-Isoform antibody (C-Term) (STJ70985)

SKU:
STJ70985-100

£312.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC/IF/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-TSPO/PBR-Isoform (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:128000.
WB: Approx 17kDa band observed in Human Breast cancer lysates and approx 16kDa in Human Ovary and Skin lysates, and in lysates of cell line A431 (calculated MW of 18.8kDa according to NP_
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: TSPO
Gene ID: 706
Uniprot ID: TSPO_HUMAN
Immunogen Region: C-Term
Accession Number: NP_000705.2
Specificity: This antibody is expected to recognise one isoform (NP_000705.2) only.
Immunogen Sequence: RDNHGWRGGRRLPE
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides.
Protein Name Translocator Protein
Mitochondrial Benzodiazepine Receptor
Pkbs
Peripheral-Type Benzodiazepine Receptor
Pbr
Database Links Reactome: R-HSA-196108
Cellular Localisation Mitochondrion Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Translocator Protein antibody
Anti-Mitochondrial Benzodiazepine Receptor antibody
Anti-Pkbs antibody
Anti-Peripheral-Type Benzodiazepine Receptor antibody
Anti-Pbr antibody
Anti-TSPO antibody
Anti-BZRP antibody
Anti-MBR antibody

Information sourced from Uniprot.org

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