• Confocal imaging of U-2 OS cells using PBR/TSPO Rabbit monoclonal antibody (STJ11102178, dilution 1:100) (Red). The cells were counterstained with Alpha-Tubulin Mouse monoclonal antibody (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
  • Confocal imaging of NIH/3T3 cells using PBR/TSPO Rabbit monoclonal antibody (STJ11102178, dilution 1:100) (Red). The cells were counterstained with Alpha-Tubulin Mouse monoclonal antibody (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
  • Immunohistochemistry analysis of PBR/TSPO in paraffin-embedded human colon using PBR/TSPORabbit monoclonal antibody (STJ11102178) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using PBR/TSPO Rabbit monoclonal antibody (STJ11102178) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-TSPO antibody (70-169) [S8MR] (STJ11102178)

SKU:
STJ11102178

£146.50 - £639.50
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Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-PBR (70-169) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S8MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TSPO
Gene ID: 706
Uniprot ID: TSPO_HUMAN
Immunogen Region: 70-169
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 70-169 of human PBR/TSPO (P30536).
Immunogen Sequence: ELGGFTEKAVVPLGLYTGQL ALNWAWPPIFFGARQMGWAL VDLLLVSGAAAATTVAWYQV SPLAARLLYPYLAWLAFTTT LNYCVWRDNHGWRGGRRLPE
Tissue Specificity Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides.
Protein Name Translocator Protein
Mitochondrial Benzodiazepine Receptor
Pkbs
Peripheral-Type Benzodiazepine Receptor
Pbr
Database Links Reactome: R-HSA-196108
Cellular Localisation Mitochondrion Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Translocator Protein antibody
Anti-Mitochondrial Benzodiazepine Receptor antibody
Anti-Pkbs antibody
Anti-Peripheral-Type Benzodiazepine Receptor antibody
Anti-Pbr antibody
Anti-TSPO antibody
Anti-BZRP antibody
Anti-MBR antibody

Information sourced from Uniprot.org

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