Anti-TSPO antibody (100-150) {FITC} (STJ503431)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 100-150 on 18 kDa mitochondrial benzodiazepine receptor protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-TSPO (100-150) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.60-0.65 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TSPO |
| Gene ID | 706 |
| Uniprot ID | TSPO_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 100-150 on 18 kDa mitochondrial benzodiazepine receptor protein. |
| Immunogen Region | 100-150 |
Additional Info
| Tissue Specificity | Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. |
| Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
| Protein Name | Translocator ProteinMitochondrial Benzodiazepine ReceptorPkbsPeripheral-Type Benzodiazepine ReceptorPbr |
| Database Links | Reactome: R-HSA-196108 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Translocator Protein antibodyAnti-Mitochondrial Benzodiazepine Receptor antibodyAnti-Pkbs antibodyAnti-Peripheral-Type Benzodiazepine Receptor antibodyAnti-Pbr antibodyAnti-TSPO antibodyAnti-BZRP antibodyAnti-MBR antibody |
Information sourced from Uniprot.org