| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TSPAN15 (110-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TSPAN15 |
| Gene ID: |
23555 |
| Uniprot ID: |
TSN15_HUMAN |
| Immunogen Region: |
110-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 110-220 of human TSPAN15 (NP_036471.1). |
| Immunogen Sequence: |
GVVALTFRNQTIDFLNDNIR RGIENYYDDLDFKNIMDFVQ KKFKCCGGEDYRDWSKNQYH DCSAPGPLACGVPYTCCIRN TTEVVNTMCGYKTIDKERFS VQDVIYVRGCT |
| Function | Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity. |
| Protein Name | Tetraspanin-15Tspan-15Tetraspan Net-7Transmembrane 4 Superfamily Member 15 |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLate Endosome Membrane |
| Alternative Antibody Names | Anti-Tetraspanin-15 antibodyAnti-Tspan-15 antibodyAnti-Tetraspan Net-7 antibodyAnti-Transmembrane 4 Superfamily Member 15 antibodyAnti-TSPAN15 antibodyAnti-NET7 antibodyAnti-TM4SF15 antibodyAnti-UNQ677 antibodyAnti-PRO1311 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
